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- DOI 10.18231/j.johs.v.12.i.2.7
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CrossMark
Efficacy of moringa oleifera as a local drug delivery agent in the treatment of chronic periodontitis: A randomized controlled trial
- Author Details:
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Gautham Sharma *
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Swati Setty
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Kaveri G.S.
Gautham Sharma *
Swati Setty
Aim: To evaluate the efficacy of chitosan chips with Moringa oleifera (MO) and chitosan chips without MO for treating chronic periodontitis.
Materials and Methods: LDD chips were made with 10% MO, 2% chitosanPEG400.A total of 38 sites of chronic periodontitis patients received LDD chips with MO, and another group of 38 sites received LDD chips without MO. The clinical parameters were assessed at baseline, 1 month, and 3 months. Radiographic alveolar bone levels were assessed at baseline and 3 months in Group I only.
Results: Group I exhibited a mean plaque index of 0.45 at one month, improving significantly to 0.45 by the third month (P < 0.001), while Group II's mean decreased from 0.65 to 0.29. The mean gingival index for Group I improved from 0.39 to 0.45, and for Group II from 0.08 to 0.29, both showing significant changes (P < 0.001). Notably, Group I had a significant reduction in probing pocket depth, from 5.26mm at one month to 4.26mm at three months (P < 0.001), outperforming Group II’s results.
Conclusion: Moringa oleifera in chitosan chips may be an effective natural treatment for chronic periodontitis. The study shows significant improvements in clinical parameters such as plaque index, gingival index, and probing pocket depth in the Moringa group, suggesting its potential to enhance treatment outcomes in periodontal care. Further exploration of its applications is encouraged.
Clinical Significance: This study underscores the potential of Moringa oleifera in chitosan chips for treating chronic periodontitis. Significant improvements in clinical parameters, such as plaque index, gingival index, and probing pocket depth in the Moringa group, suggest it may enhance treatment outcomes. This natural agent offers a promising adjunct option for dental professionals, supporting better management of chronic periodontitis and encouraging further exploration of natural products in periodontal care.
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