POST-EXTRACTION INFLAMMATORY MYOFIBROBLASTIC TUMOR OF MAXILLA – A RARE ORAL PRESENTATION

Authors: Pavithra Ramasamy, Sunita Gupta, Sujoy Ghosh, Priya Kumar

DOI: 10.18231/j.johs.12289.1760075008

Keywords: inflammatory myofibroblastic tumor, inflammatory pseudotumor, oral cavity, maxilla, myofibroblast, smooth muscle actin

Abstract: Inflammatory myofibroblastic tumor (IMT) is a rare, benign, locally aggressive tumor that shows uncertain malignant potential. Based on the spectrum of histological appearances, it is known by different names, most commonly plasma cell granuloma, inflammatory pseudotumor, myofibroblastoma, inflammatory myofibrohistiocytic tumor, xanthogranuloma, fibrous xanthoma, etc., and most recently as inflammatory myofibroblastic tumor. The etiology is non-specific, and suggested to be a result of an inflammatory response to unknown factors. It is particularly uncommon in the oral cavity, with a PubMed literature search identifying only two documented cases reported at post-extraction sites to date, with the most common clinical differential diagnosis of peripheral reactive lesions such as pyogenic granuloma, peripheral giant cell granuloma, peripheral ossifying fibroma. This article presents a rare case of an inflammatory myofibroblastic tumor with an aggressive clinical presentation, arising at the post-extraction site of the right maxilla in a 50-year-old female patient. We also aim to discuss its etiopathogenesis, clinical and radiologic features, histopathological correlations, and management strategies.